News

Cambridge researchers have discovered why living in a disadvantaged neighbourhood may be linked to an increase in an individual’s risk of dementia.In research published today, they show how it is associated with damage to brain vessels – which can affect cognition – and with poorer management of lifestyle factors known to increase the chances of de…

The 10 organisations in Great Britain that carry out the highest number of animal procedures - those used in medical, veterinary and scientific research - have released their annual statistics today."Animal research... is an essential step in the development of new medicines, vaccines and treatments for both humans and animals."Jon SimonsThe statis…

Problems with the brain’s waste clearance system could underlie many cases of dementia and help explain why poor sleep patterns and cardiovascular risk factors such as high blood pressure increase the risk of dementia.A study led by researchers at the University of Cambridge found that impaired movement of cerebrospinal fluid (CSF) – the clear liqu…

A Cambridge patient has become the first person in Europe to receive cutting-edge histotripsy treatment outside of a clinical trial, after the technology was fast-tracked by the Government - marking a major milestone in NHS cancer care.The pioneering procedure, which uses ultrasound energy to destroy tumours, took place at Addenbrooke’s Hospital, w…

Four cutting-edge University of Cambridge research projects are to receive funding from UKRI to grow into market-leading products and services.A total of 48 projects from across the UK are receiving funding from a new £9 million proof of concept programme to support and accelerate the development of new or improved technologies, products, processes…

Researchers find different genetic profiles related to two trajectories that autistic children tend to follow. One linked to early diagnosis, and communication difficulties in infancy. The other linked to later diagnosis, increased social and behavioural difficulties in adolescence, and higher rates of conditions like ADHD, depression, and PTSD.An …

Scientists have, for the first time, directly visualised and quantified the protein clusters believed to trigger Parkinson’s, marking a major advance in the study of the world’s fastest-growing neurological disease.These tiny clusters, called alpha-synuclein oligomers, have long been considered the likely culprits for Parkinson’s disease to start d…

Scientists behind the trial say they are “on the brink of a new class of treatments” and that the findings take us another step closer to stopping disease progression in MS.A combination of metformin, a common diabetes drug, and clemastine, an antihistamine, can help repair myelin – the protective coating around nerves, which gets damaged in multip…

When Bifidobacterium breve, widely available in probiotic drinks, is present in the gut of pregnant females it boosts the placenta’s production of pregnancy hormones to reduce the likelihood of complications like preeclampsia and miscarriage.Research led by the University of Cambridge has found the first clear evidence that the ‘good’ gut bacteria …

Three Cambridge researchers are among 77 early-career researchers who have been awarded a total of £120 million to lead vital research, collaborate with innovators and develop their careers as the research and innovation leaders of the future.Cambridge researchers Dr Claudia Bonfio, Dr Akshay Deshmukh and Dr Elizabeth Radford have been awarded UKRI…

A University of Cambridge study of adult mammary gland development has revealed new genes involved in breastfeeding, and provided insights into how genetic changes may be associated with breastfeeding disorders and postpartum breast cancers.In a study in mice, researchers have identified genes associated with the dramatic transformation of the mamm…

Researchers have developed a material that can sense tiny changes within the body, such as during an arthritis flare-up, and release drugs exactly where and when they are needed.The squishy material can be loaded with anti-inflammatory drugs that are released in response to small changes in pH in the body. During an arthritis flare-up, a joint beco…

WHO? Professor Tuomas Knowles, world-leading expert on proteins and founder of five spinout companies, all of which apply breakthroughs in protein science to real-world problems.WHAT?Xampla is replacing the most polluting plastics with plant-based materials; Transition Bio applies fundamental biology to drug discovery; Ride Therapeuticsdevelops sol…

Researchers have captured the first clear view of the hidden architecture that helps shape a simple multicellular organism, showing how cells work together to build complex life forms.In a study published in the journal Proceedings of the National Academy of Sciences (PNAS), a team of British and German scientists revealed the structure of the extr…

Immune cells released from bone marrow in the skull in response to chronic stress and adversity could play a key role in symptoms of depression and anxiety, say researchers.The discovery – found in a study in mice – sheds light on the role that inflammation can play in mood disorders and could help in the search for new treatments, in particular fo…